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METABIOSONA
DESCRIPTION
Dexamethasone in injectable solution.
TECHNICAL PROPERTIES
Dexamethasone is an artificial corticosteroid derived from hydrocortisone. It is well absorbed and diffused and it is removed in urine. It decreases the vascular and cellular reactions that are part of the inflammatory processes, modifying the lymphocyte function.
It increases the glyconeogenesis, proteiN catabolism, lipid synthesis and the sodium and water retention. Dexamethasone acts mainly at two levels: the tissular and the metabolic level.
At tissular level it operates as an anti-inflammatory by inhibiting A2 phospholipase, which frees araquidonic acid from the membrane lipids. Basically it decreases the vascular and cellular reactions of processes derived from an inflammation. It also acts as an immunosupressor.
At metabolic level it stimulates the neoglycogenesis, activates the catabolism of proteins, increases lipid biosynthesis, retains sodium and frees potassium.
INDICATIONS AND SPECIES
Indicated for pigs, sheep, goats and cattle with the following indications:
- Anti-inflammatory in processes with a non infectious origin.
- Anti-allergic in immune diseases.
- Treatment of ketosis, tetanus and vitulary fever of nutritional origin.
ENGOREPROD 471-2456 20080709
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