ESTREPTOS
DESCRIPTION ESTREPTOS is an antibiotic association of erythromycin and streptomycin injectable and oral extemporaneous solution. TECHNICAL PROPERTIES
ESTREPTOS is an antibiotic association with a high effectiveness against respiratory diseases with a mycoplasmic base, complicated by external germs (Streptococcus, Pasteurella, E. coli and Moraxella and others).
Erythromycin is a macrolid antibiotic that is quickly absorbed orally (the maximum plasma concentrations are reached one hour after administration) and it is diffused in tissues and blood fluids. As with all macrolides it is removed for more than 60% through the enterohepatic cicle (kidney and bile). It inhibits the protein synthesis by binding in the 50S subunit of the bacterial ribosome and therefore blocking the growing peptide chain. Erythromycin is active against Gram positive bacteria such as Staphylococcus, Mycoplasma, Streptococcus, Corynebacterium and Clostridium.
Streptomycin is an antibiotic belonging to the oligosaccharides group and stops bacterial growth by damaging cell membranes and inhibiting protein synthesis. Specifically, it binds to the 16S rRNA of the bacterial ribosome, which prevents the release of the growing protein. Its spectrum is basically Gram negative bacteria, especially Pasteurella, Shigella, coliforms and Pseudomona. Some Gram positive germs are also sensitive; like Corynebacterium, Streptococcus and Staphylococcus.
INDICATIONS AND SPECIES
Indicated for poultry, pigs, sheep, goats and cattle with the following indications:
- Pneumoenteritis.
- Pasteurelosis.
- Pneumonia.
- C.R.D.
ENGOREPROD 471-2427 20080516
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